Evaluation of Microbiologic and Hematologic Parameters and E-Selectin As Early Predictors for Outcome of Neonatal Sepsis (Report) - Archives of Pathology & Laboratory Medicine

Evaluation of Microbiologic and Hematologic Parameters and E-Selectin As Early Predictors for Outcome of Neonatal Sepsis (Report)

By Archives of Pathology & Laboratory Medicine

  • Release Date: 2009-08-01
  • Genre: Health & Fitness
Evaluation of Microbiologic and Hematologic Parameters and E-Selectin As Early Predictors for Outcome of Neonatal Sepsis (Report) book review score

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Evaluation of Microbiologic and Hematologic Parameters and E-Selectin As Early Predictors for Outcome of Neonatal Sepsis (Report) Archives of Pathology & Laboratory Medicine Book Review Score: ★★★★★ 5/5 stars

Morbidity and mortality from neonatal sepsis are major health problems. Early warning signs and symptoms are often nonspecific and can easily be confused with those from noninfective causes. Timely diagnosis of neonatal sepsis is critical because, in this age group, the illness can progress more rapidly and have a higher mortality rate than in other age groups. (1) Microbiologic culture results are usually unavailable until a minimum of 48 to 72 hours after the specimen reaches the laboratory; therefore, early identification of infected cases is a major diagnostic problem in newborn infants. Thus, a reliable infection marker or a set of markers are needed to promptly and accurately identify the infected cases so that treatment can be started without delay. Equally difficult is the exclusion of infection in infants with suspected sepsis. Continuation of broad-spectrum antibiotics for presumptive bacterial infection frequently

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