Roy Lawrence, a young African-American physician, is on trial at his hospital for practicing bad medicine. During the trial, Roy's accuser, chief of staff Donald Horsmann, is violently killed after leaving his mistress' apartment. As the only suspect, Roy is immediately arrested and put on trial, where a vicious prosecutor and the judge want nothing more than to see him fry. Barry Goodman, a Boston attorney and Roy's former Harvard roommate, takes up Roy's cause and tries to prove his innocence.
Meanwhile, Courtney Williams, the daughter of a patient killed during surgery by Horsmann, has reason to believe her brother, Jamal, was the hired killer. Together Courtney and Barry attempt to discover the identity of the mastermind. Unfortunately the trap they set goes awry and leaves Courtney nearly fatally wounded in the hospiutal ICU. Courtney is the only one who can clear Roy, yet she is unconscious and unguarded in the ICU, at the mercy of the real killer while Roy is trapped in prison.