Attention-deficit hyperactivity disorder (ADHD) has some-times devastating effects in the daily lives of the 25 million, or five percent of the U.S. population, who suffer from it. Children with ADHD are at greater risk than children without ADHD for substance abuse and delinquency. And, 65 percent of those diagnosed with childhood ADHD have symptoms as adults. ADHD treatment requires a multi-modal approach: medication, behavior modification, lifestyle changes, and therapy. While stimulants such as methylphenidate and amphetamine are thought to be most effective in treating ADHD, concerns about sudden unexplained death, adverse psychiatric effects, addiction, and abnormal growth have driven the introduction of "non-stimulant" therapies.